Retrospective Investigation of Brainstem Volume and Craniovertebral Junction Morphometry in Migraine Patients

Aim: Migraine, a complex, multifactorial neurovascular brain disorder, might cause several functional and morphometric changes in the brain. Despite many studies, consensus has not emerged on its pathophysiology, it is fully elucidated so far. Recently, changing structures migraine with aura been attracting attention of scientific periphery. The brainstem critical region pathogenesis migraine. Another transition point craniovertebral junction. Regional pathologies trigger off neurodegenerative neurological diseases by affecting hydrodynamics. Moreover, there insufficient data relationship between present study aimed to make volumetric analysis volume without aura, perform some angular linear measurements junction, evaluate effects these parameters patients. Material Methods: retrospectively analyzed Magnetic Resonance Images 108 patients (aged 18 65). Their volumes were measured using volBrain (online MRI volumetry system). Also, junctions derived from images. obtained transferred SPSS 22 package program analyzed. Results: mean was 17.21±2.79 cm3 group, 17.33±2.48 19.27±2.76 control group. There no statistically significant difference groups (p>0.05). both (p<0.05). Furthermore, clivus-canal angle significantly different patient groups. Conclusion: found that lower (with aura) than angles show this issue should be more comprehensively studied.